martinstronis65
U P L O A D E R
Learn Bioinformatics - Beginner To Master Through Projects
Published 12/2024
MP4 | Video: h264, 1920x1080 | Audio: AAC, 44.1 KHz
Language: English | Size: 4.82 GB | Duration: 8h 7m
Master Bioinformatics Through Projects: Master the Sequence, Genomics, Proteomics, Transcriptomics, and RNA-Seq Analysis
What you'll learn
Gain a comprehensive understanding of bioinformatics and its subfields, including genomics, proteomics, transcriptomics, metabolomics, and pharmacogenomics.
Develop practical skills to retrieve and analyze biological data using popular bioinformatics databases and tools.
Build a strong foundation in bioinformatics programming and command-line skills for advanced data analysis.
Understand the scope and importance of bioinformatics in modern biology.
Differentiate between the various subfields of bioinformatics and their applications.
Identify the skills required to pursue a career in bioinformatics.
Learn to navigate and extract data from primary, secondary, and derived bioinformatics databases like NCBI, PDB, Uniprot, and GEO.
Develop proficiency in performing practical searches and retrieving biological data for analysis.
Gain an overview of essential bioinformatics tools and programming languages like Python, R, and Perl.
Understand the role of bioinformatics tools in solving biological questions.
Perform pairwise and multiple sequence alignment to understand genetic similarity.
Conduct homology searches and interpret results using tools like BLAST.
Predict gene structures, annotate genomes, and analyze gene functions.
Visualize genomic data and locate genes on chromosomes.
Analyze protein motifs, domains, and interactions in protein-protein interaction (PPI) networks.
Calculate protein physical parameters using proteomics tools.
Build and interpret phylogenetic trees to study evolutionary relationships.
Use tools like IQ-TREE and iTOL for evolutionary analysis.
Navigate the Linux file system and execute bioinformatics workflows using basic Linux commands.
Write bash scripts to automate bioinformatics analyses.
Analyze and interpret transcriptomics data, including microarray datasets.
Conduct gene expression studies to identify significant patterns.
Retrieve, preprocess, and align RNA-Seq data to reference genomes.
Perform quantification and analysis of RNA-Seq data using command-line tools.
Develop problem-solving skills through project-based learning.
Apply bioinformatics methods to real-world biological datasets.
Be prepared for advanced studies or a professional career in bioinformatics.
Requirements
Familiarity with using a computer, installing software, and navigating the internet.
A basic understanding of biology or life sciences concepts (e.g., DNA, RNA, proteins) is helpful but not mandatory.
A desire to learn bioinformatics through hands-on projects and data-driven approaches.
A laptop or desktop computer (Windows, Mac, or Linux).
Stable internet connection for accessing databases, tools, and course materials.
Familiarity with basic command-line interfaces or programming is a bonus but not required-everything will be taught from scratch.
Description
Learn Bioinformatics - Beginner to Master Through Projects is a comprehensive and hands-on course designed for anyone looking to delve into the exciting field of bioinformatics. Whether you are a beginner, an intermediate learner, or someone exploring a career switch, this course equips you with the essential knowledge and practical skills to excel in the field. Through real-world projects and step-by-step guidance, you'll explore the vast landscape of bioinformatics, from foundational concepts to advanced applications.What Will You Learn?This course offers a structured and immersive learning experience that covers a wide range of topics:Foundations of BioinformaticsUnderstand what bioinformatics is and its critical role in modern biology.Explore various subfields like genomics, proteomics, transcriptomics, metabolomics, structural bioinformatics, pharmacogenomics, and computational biology.Learn about the latest trends and required skills in computational biology.Data Retrieval from Bioinformatics DatabasesGain proficiency in using key bioinformatics databases, including NCBI, PDB, Uniprot, and GEO.Learn to retrieve, interpret, and analyze biological data effectively.Bioinformatics Tools and ProgrammingExplore essential tools and programming languages used in bioinformatics, such as Python, R, and Linux commands.Understand how these tools are applied to solve real-world biological problems.Sequence AnalysisMaster sequence alignment techniques, including pairwise and multiple sequence alignments.Conduct homology searches using BLAST and interpret the results.Functional Genomics and ProteomicsPerform gene prediction, genome annotation, and functional enrichment analysis.Analyze protein motifs, domains, and protein-protein interaction (PPI) networks.Evolutionary BioinformaticsBuild and interpret phylogenetic trees to explore evolutionary relationships using tools like IQ-TREE and iTOL.Command-Line BioinformaticsDevelop strong Linux skills to navigate file systems, install tools, and write bash scripts.Automate bioinformatics workflows for efficient data analysis.Transcriptomics and RNA-Seq Data AnalysisAnalyze transcriptomics data, including microarray datasets.Perform RNA-Seq data retrieval, preprocessing, alignment, and quantification using Linux.How Is This Course Structured?The course is divided into 10 sections, each focusing on a specific area of bioinformatics. Each section includes:Engaging Lectures: Clear and concise explanations of concepts with real-world examples.Practical Demonstrations: Hands-on tutorials to help you apply what you learn.Projects: End-of-section projects that reinforce your learning and provide practical experience.By the end of this course, you'll complete 10 real-world projects, such as:Exploring bioinformatics subfields.Retrieving and analyzing biological data from major databases.Conducting sequence alignments and phylogenetic analysis.Performing genome annotation, gene prediction, and functional enrichment.Analyzing transcriptomics and RNA-Seq data.Who Should Take This Course?This course is designed for:Beginners and intermediate learners in bioinformatics.Students and researchers in biology, biotechnology, or related fields.Professionals exploring a career switch into bioinformatics.Programmers and data analysts interested in applying their skills to biological data.Anyone passionate about learning bioinformatics through hands-on projects.Why Choose This Course?Practical Approach: Learn bioinformatics through 10 real-world projects and practical demonstrations.Comprehensive Content: Gain expertise in various aspects of bioinformatics, including genomics, proteomics, transcriptomics, and more.Beginner-Friendly: Minimal prerequisites and step-by-step guidance make this course accessible to everyone.Career-Oriented: Acquire skills that are highly sought after in the bioinformatics industry.What Do You Need to Start?All you need is a computer, an interest in biology, and a desire to learn. No prior experience in bioinformatics or programming is required-we'll guide you every step of the way.Enroll now and start your journey toward becoming a bioinformatics expert. Unlock the power of biological data and solve real-world challenges with confidence!
Overview
Section 1: Introduction to Bioinformatics and Subfields
Lecture 1 Introduction to Bioinformatics
Lecture 2 Genomics
Lecture 3 Proteomics
Lecture 4 Transcriptomics
Lecture 5 Metabolomics
Lecture 6 Structural Bioinformatics
Lecture 7 Pharmacogenomics
Lecture 8 Computational Biology
Lecture 9 Other Subfields of Bioinformatics
Lecture 10 Trends In Computational Biology
Lecture 11 Skills Needed For Bioinformatics Field
Section 2: Bioinformatics Databases and Data Retrieval
Lecture 12 Introduction To Bioinformatics Databases
Lecture 13 Primary Databases Introduction And NCBI Practical
Lecture 14 EMBL and DDBJ Database Practical
Lecture 15 Introduction to secondary databases
Lecture 16 PDB database
Lecture 17 Uniprot Database
Lecture 18 GEO Database
Lecture 19 Derived Databases and Practical
Lecture 20 Conclusion and Project Insights
Section 3: Bioinformatics Tools and Programming languages
Lecture 21 Bioinformatics Tools and Programming languages
Section 4: Sequence Analysis
Lecture 22 Sequence alignment and Pairwise sequence alignment
Lecture 23 Practical Pairwise sequence alignment
Lecture 24 Multiple sequence alignment
Lecture 25 Practical Multiple sequences alignment
Lecture 26 Homology searching and blast
Lecture 27 Practical Blast and homology searching
Section 5: Functional Genomics
Lecture 28 Introduction to Genomics
Lecture 29 Gene prediction analysis
Lecture 30 Gene structure prediction
Lecture 31 Genome annotation and visualization
Lecture 32 Gene location on chromosome
Lecture 33 Gene functional enrichment analysis
Section 6: Proteomics
Lecture 34 Introduction to Proteomics
Lecture 35 Motifs analysis
Lecture 36 Domains Analysis
Lecture 37 PPI Networks
Lecture 38 Protein physical parameters
Section 7: Evolutionary Bioinformatics
Lecture 39 Introduction to evolutionary Bioinformatics
Lecture 40 Practical building Phylogenetic trees
Section 8: Command Line Bioinformatics
Lecture 41 Introduction to Linux
Lecture 42 Environment setup on Windows
Lecture 43 Navigating the Linux file system
Lecture 44 Basic Linux commands for bioinformatics
Lecture 45 Installing bioinformatics tools
Lecture 46 Bash scripting for bioinformatics
Section 9: Transcriptomics
Lecture 47 Introduction to Transcriptomics
Lecture 48 Microarray Data analysis
Section 10: RNA-Seq Data Analysis
Lecture 49 Introduction to RNA-Seq Data Analysis
Lecture 50 Retrieving RNA-Seq Data
Lecture 51 Preprocessing of RNA-Seq Data
Lecture 52 Indexing And Alignment To Reference Genome
Lecture 53 Quantifications Of BAM Files
This course is perfect for anyone looking to build a strong foundation in bioinformatics through hands-on learning and real-world projects.,Students or professionals with little to no prior experience in bioinformatics who want to start their journey in this field.,Those with some exposure to bioinformatics concepts who want to deepen their understanding and learn advanced techniques through practical projects.,Biology, biotechnology, or related field students and researchers looking to integrate bioinformatics into their studies or work.,Individuals exploring bioinformatics as a potential career path or looking to upskill for opportunities in genomics, proteomics, computational biology, and related areas.,Computer scientists, programmers, or data analysts interested in applying their technical skills to biological data and bioinformatics challenges.,Learners who prefer project-based, hands-on education to theoretical coursework and want to work with real-world biological data.
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